{"id":307,"date":"2018-11-06T15:37:59","date_gmt":"2018-11-06T13:37:59","guid":{"rendered":"https:\/\/www.labistanbul.com.tr\/?p=307"},"modified":"2022-07-29T14:32:32","modified_gmt":"2022-07-29T11:32:32","slug":"mthfr-mutation-test","status":"publish","type":"post","link":"https:\/\/www.labistanbul.com.tr\/en\/mthfr-mutation-test\/","title":{"rendered":"MTHFR Mutation Test"},"content":{"rendered":"

\"\"What is the MTHFR mutation test?<\/h2>\n

In MTHFR gene mutation, which is one of the hereditary thrombophilias (coagulation disorders), homocysteine \u200b\u200blevel increases and a tendency to clot occurs as a result of mutation in the methylenetetrahydrofolate enzyme gene. The most common C677T mutation is seen. It is seen in 2-15% of societies. Hyperhomocysteinemia may also occur for reasons other than MTHFR gene mutation. In hyperhomocysteinemia, the tendency to both arterial and venous thrombosis increases.<\/p>\n

\n

Thermolable MTHFR and Hyperhomocysteinemia<\/strong><\/h2>\n

High levels of the amino acid homocysteine \u200b\u200bare another independent risk factor for venous thrombosis that have been identified in recent years. There is a 2-3 fold increase in the risk of VTE in patients with hyperhomocysteinemia, which can constitute up to 5% of the population.<\/p>\n

Common causes of hyperhomocysteinemia include inadequate intake of folate, vitamins B6 or B12, and inherited defects of cystathionine synthase or methylenetetrahydrofolate reductase (mthfr) enzymes that play a role in homocysteine \u200b\u200bmetabolism.<\/p>\n

While homocysteine \u200b\u200bmeasurements are applied in the examination of patients with arterial and venous thrombophilia, thermolabile-MTHFR mutation analysis, which is reported to be found in 5-15% of the normal population, is recommended in patients with pregnancy complications and in patients with hyperhomocysteinemia of unknown cause and their relatives.<\/p>\n

\n

In how many days MTHFR Mutation Test comes out:<\/strong>
\nThe MTHFR Mutation Test is used with a blood sample. The reporting period of the test is between 15-20 days on average. For the test, hunger or satiety does not matter.<\/p>\n","protected":false},"excerpt":{"rendered":"

What is the MTHFR mutation test? In MTHFR gene mutation, which is one of the hereditary thrombophilias (coagulation disorders), homocysteine \u200b\u200blevel increases and a tendency to clot occurs as a result of mutation in the methylenetetrahydrofolate enzyme gene. The most common C677T mutation is seen. It is seen in 2-15% of societies. Hyperhomocysteinemia may also […]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[18],"tags":[],"class_list":["post-307","post","type-post","status-publish","format-standard","hentry","category-genetic-tests"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/www.labistanbul.com.tr\/en\/wp-json\/wp\/v2\/posts\/307","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.labistanbul.com.tr\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.labistanbul.com.tr\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.labistanbul.com.tr\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.labistanbul.com.tr\/en\/wp-json\/wp\/v2\/comments?post=307"}],"version-history":[{"count":0,"href":"https:\/\/www.labistanbul.com.tr\/en\/wp-json\/wp\/v2\/posts\/307\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.labistanbul.com.tr\/en\/wp-json\/wp\/v2\/media?parent=307"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.labistanbul.com.tr\/en\/wp-json\/wp\/v2\/categories?post=307"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.labistanbul.com.tr\/en\/wp-json\/wp\/v2\/tags?post=307"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}