Microdeletion Test
Microdeletion TestY Microdeletion Test
It has been determined that sperm problems ranging from severe sperm production disorders to azoospermia develop as a result of the deletion of genes on the long arm of the Y chromosome or the breakage of these regions in infertile men. When sperm are obtained from men with Y microdeletion, the chance of fertilization and pregnancy in their spouses is the same as in men without other chromosomal disorders. However, it should not be forgotten that sons born to men with Y microdeletion will also have infertility problems in the future, as they will also have a Y chromosome from them.
Y Microdeletion Test Who Requests Y Microdeletion Test?
Hormone analyzes should be performed in cases of sperm count 1 million/ml, sexual dysfunction, endocrine disorder or severe decrease in testicular size according to examination findings. In azoospermic men with sperm count less than 5 million/ml and due to sperm production disorder in the testis, genetic investigations should be applied depending on clinical findings.
Today, peripheral karyotype analysis, Y chromosome microdeletion test and cystic fibrosis gene mutation analysis are performed in men due to infertility. These tests should not be requested from everyone, but from patients undergoing advanced research. These are simple tests that look at the blood taken from your arm, it can take time to result.