1.25 dihydroxy Vitamin D Test

Also known as	1,25 (OH) Vitamin D, 1,25-Dihydroxy Vitamin D, 1,25-Dihydroxycholecalciferol, Vitamin D, 1,25-Dihydroxy
Preparation	No special preparation is required.
Test results	3 or 4 days. It may take longer due to holiday or lab repeat delays.

The Vitamin D 25-Dihydroxy test measures the active form of Vitamin D produced in the liver and kidneys through the conversion of Vitamin D 25-Hydroxy. This test is not typically used as a routine measure to assess whether a person has a vitamin D deficiency because it can show normal results even if a person has a general deficiency.

This test measures the bioactive form of vitamin D. It is used in the differential diagnosis of hypocalcemia and to monitor patients with renal osteodystrophy or chronic renal failure. This test is not suitable for diagnosing vitamin D deficiency and monitoring supplementation in most patients. Vitamin D 25-Hydroxy Blood Test is the recommended test for these purposes.

In some cases, the Vitamin D 1,25 Dihydroxy Blood Test is ordered if an abnormality associated with the enzyme that converts 25-hydroxyvitamin D to 1,25-dihydroxyvitamin D or kidney disease is suspected. Low levels may be indicative of the latter, as this is usually one of the first changes to occur in patients with early kidney failure.

This test may also be ordered to aid in diagnosis or Parathyroid disorder or kidney failure. It also helps diagnose primary hyperparathyroidism, hypoparathyroidism, pseudohypoparathyroidism, renal osteodystrophy and vitamin D resistant rickets.

Calcitriol is a type of vitamin D used to treat and prevent low blood calcium levels in patients whose kidneys or parathyroid glands (glands in the neck that secrete natural substances to control the amount of calcium in the blood) are not working. normally. A low blood calcium level can cause bone disease.

A low 1,25-dihydroxyvitamin D level can be seen in kidney disease and is one of the earliest changes to occur in people with early kidney failure.

An elevated 1,25-dihydroxyvitamin D can occur when there is an excess of parathryoid hormone or when there are diseases that can make 1,25-dihydroxyvitamin D outside the kidneys, such as sarcoidosis or some lymphomas.